Body Weight, Body Mass Index, and Blood Glucose of Long-Tailed Monkeys (Macaca fascicularis) Given High-Energy Feed and Liquid Nicotine

Author: Chusnul Choliq, Irma Herawati Suparto, Septi Iriani, Dondin Sajuthi

Abstrak

Certain doses of nicotine have been reported to have an effect on decreased appetite in mice, but have not been reported in long-tailed monkey animal models. Therefore this study aimed to determine the effect of nicotine on body weight, body mass index (BMI) and blood glucose levels of long-tailed monkeys (Macaca fascicularis) who were given a high-energy diet for three months. Ten adult male monkeys were randomly divided into two groups. The first group was fed with the main ingredients of beef fat and the second group with commercial monkey chow. Nicotine liquid is added to both feeds with a dose of 0.75 mg / kg body weight. The design used in this study is a completely randomized design (nested) in time. Data collected was analyzed to determine the relationship between time and treatment. Measurements were taken every four weeks on body weight, body mass index and blood glucose levels. The results showed a decrease in body weight that was not significant (P> 0.05), but BMI and blood glucose levels decreased significantly in the first group (P <0.05). It was concluded that the administration of liquid nicotine in adult male long-tailed monkeys with a high-energy diet could significantly reduce BMI and blood glucose levels, but not significantly to body weight.

Keywords: body weight, body mass index, blood glucose, long-tailed monkey, nicotine

 

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