Screening of Endophytic Fungi from Chlorophyta and Phaeophyta for Antibacterial Activity
Author : A.C Rahaweman, J Pamungkas, H Madduppa, C Thoms, K Tarman
Abstract. Chlorophyta and Phaeophyta macroalgae are important sources of secondary metabolites with pharmaceutically relevant antibacterial, antifungal and antiviral bioactivities. Oftentimes, these algae-derived compounds are, in fact, produced by endophytic fungi living inside the macroalgal tissue. Numerous studies have shown that endophytic fungi can produce a broad range of active metabolites such as terpenes, alkaloids, and quinones. The aim of the present study was to screen fungal strains isolated from a variety of Caulerpa spp., Halimeda spp., and Sargassum spp. for antibacterial activity against Staphylococcus aureus and Escherichia coli. Thirteen morphologically different isolates were tested. Two of them showed pronounced activity against S. aureus in agar diffusion assays.
Keywords: Antibacterial activity, Antibiotics, Chlorophyta, Endophytic fungi, Macroalgae, Phaeophyta